Noted Pancreatic Cancer Researcher Dr. Daniel Von Hoff to Present at the Spring 2013 Donald K. Buffmire Lecture

Tuesday, March 19, 2013 - 12:00pm to 1:00pm
Renowned pancreatic cancer researcher and cancer drug developer Daniel D. Von Hoff, MD, FACP, will present ‘A Relentless Molecular Pursuit on Behalf of Patients With Refractory or Rare Cancer,a free lecture, open to the public, in Tucson, Tuesday, March 19, and in Phoenix, Wednesday, March 20. Dr. Von Hoff is physician in chief and distinguished professor with the Translational Genomics Research Institute (TGen).
Pancreatic cancer is the fourth-leading cause of death from cancer in the United States and has the worst one- and five- year survival rates of any cancer. The lecture will demonstrate how the survival rate for patients with advanced pancreatic cancer has improved through the genomic profiling of pancreatic cancer tumor cells, the characterization of tumor stroma and the study of how pancreatic cancer cells use “fuel.”
An unexpected finding while molecularly profiling patients’ cancers is that rare cancers – acinar cell, adenosquamous cell, salivary gland tumors and others – often have a single mutation or abnormality which “drives” that cancer. Using a targeted agent for treating patients with rare cancers can produce dramatic shrinkage of their cancers.
The Tucson presentation will be held Tuesday, March 19, with the lecture from noon to 1 p.m., followed by a meet-and-greet reception from 1 to 1:30 p.m. (light lunch provided), in Kiewit Auditorium, Arizona Cancer Center, 1515 N. Campbell Ave., Tucson. The Tucson event also will be broadcast live and archived on the Internet at (Please note: There is a parking fee of $1.50 per hour, cash only, in The University of Arizona Medical Center – University Campus Visitor/Patient Parking Garage, 1501 N. Campbell Ave., just south of the Arizona Cancer Center. Metered parking spaces are available in UA Zone 1 parking lot 2030, at East Mabel Street and North Martin Avenue, south of the UAMC parking garage.) For more information about the March 19 and upcoming Buffmire lectures in Tucson, contact Rebecca Parada-Anderson, UA College of Medicine – Tucson Office of Special Events, 520-626-6177, email
The Phoenix presentation will be held Wednesday, March 20, beginning with a meet-and-greet reception (featuring medical student posters representing the culmination of their four-year scholarly research projects) at 5 p.m.,followed by the lecture from 6 to 7 p.m., in Lecture Hall B102, Health Sciences Education Building, 435 N. 5th St., Phoenix. (Please note: For campus maps and detailed parking information, click here.) For the Phoenix lecture, guests are asked to register online by March 18 or RSVP to Sheila Maddox, University of Arizona College of Medicine – Phoenix, 602-827-2007, email 
The presentations are part of the Donald K. Buffmire Visiting Lectureship in Medicine series, sponsored by the Flinn Foundation.
About Dr. Von Hoff
Daniel D. Von Hoff, MD, FACP, is physician in chief and distinguished professor with the Translational Genomics Research Institute (TGen) and professor of medicine with Mayo Clinic in Phoenix; chief scientific officer for Scottsdale Healthcare’s Clinical Research Institute; and professor of medicine with the UA College of Medicine – Phoenix. He is a former director of The University of Arizona Cancer Center. He holds several other titles with national organizations and research programs.
Dr. Von Hoff’s major interest is in the development of new anticancer agents, both in the clinic and in the laboratory. He and his colleagues were involved in the early development of many of the agents now routinely used. They now are concentrating on the development of molecularly targeted therapies.
Dr. Von Hoff is widely published and in 2010 received the David A. Karnofsky Memorial Award from the American Society of Clinical Onocology for outstanding contributions to cancer research leading to significant improvements in patient care.
About the Donald K. Buffmire Visiting Lectureship in Medicine
Initiated in 1997, the Donald K. Buffmire Visiting Lectureship in Medicine series continues the Flinn Foundation’s commitment to bring to Arizona leading practitioners and thinkers in the medical field. The lectureship offers physicians, students and community members opportunities to hear from distinguished leaders in the field of medicine and medical education. In 2008, the annual lecture was expanded to a biannual event and includes presentations in both Phoenix and Tucson.
The lectureship is named for the late Donald K. Buffmire, MD, in recognition of his distinguished career as a medical practitioner in Arizona and his leadership role with the Flinn Foundation in supporting the UA College of Medicine. Dr. Buffmire, who died in July 2008 at age 85, served on the board of the Flinn Foundation for 36 years, from 1965 to 2001, including 14 years as its chair.
The Phoenix-based Flinn Foundation is a privately endowed organization that awards grants to non-profit organizations in Arizona, primarily to improve the competitiveness of the state’s biomedical research enterprise.
About the UA College of Medicine
The UA College of Medicine ( is the only allopathic medical college in Arizona. Beginning in 1967 with a class of 32 students on its Tucson campus, the college today encompasses full, four-year medical-education programs in Tucson and in Phoenix.