Drug Induced Arrhythmia - Not Just A Guy Thing

<p>Drug Induced Arrhythmia - Not Just A Guy Thing</p>

Drug Induced Arrhythmia - Not Just A Guy Thing

The University of Arizona Health Sciences Center will kick off a series of lectures on women's health research with a talk by Raymond Woosley, MD, PhD, UA Vice President for Health Sciences, and an international expert on arrhythmias and drug safety. (An arrhythmia is a change in the regular beat of the heart. The heart may seem to skip a beat or beat irregularly, very fast, very slowly or not at all.)
The University of Arizona recently received the prestigious designation as a National Center of Excellence in Women's Health (CoE), a major federal initiative to advance women's health care.

Dr. Woosley's initial research focused on the clinical pharmacology of anti-arrhythmic drugs. He helped provide the scientific underpinning of the Cardiac Arrhythmia Suppression Trial (CAST), which began in 1987 with 27 sites nationwide to test the use of anti-arrhythmic drug therapy to decrease mortality. He served as co-director of this trial, which demonstrated for the first time that although anti-arrhythmic drugs can suppress cardiac arrhythmias, they, in fact, still increase the risk of sudden death.

Dr. Woosley also conducted groundbreaking research on the medication Seldane, a popular antihistamine introduced in 1985 that was withdrawn from the market after reports that taking it in conjunction with certain drugs could cause potentially fatal abnormalities in heart rhythm. His work led to the discovery of fexofenadine, a safer version of Seldane that now is marketed under the brand name Allegra.

More recently, Dr. Woosley's research has explored why women appear to be more susceptible than men to potentially fatal arrhythmias caused by a number of prescription drugs.

What: Lecture

Speaker: Raymond Woosley, MD, PhD, UA Vice President for Health Sciences

When: Monday, Nov. 24, Noon TO 1 p.m.

Where: Kiewit Auditorium, Arizona Cancer Center, 1501 N. Campbell Ave.

Contact Information: Darla Franklin, 626-5660

EDITORS NOTE: Reporters are welcome to attend/cover this lecture.